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Results from an international IBD registry shows that steroids but not biologics (anti-TNFs) are associated with poor Covid 19 outcomes in IBD patients.
• Increasing age, comorbidities and steroid use were associated with adverse outcomes in IBD patients who contract Covid 19 infection.
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• Biologic agents (like anti-TNF antagonists) does not increase the risk of hospitalization, ICU , ventilator use or death.
•The study concluded that maintaining IBD remission with steroid sparing regimen is warranted through out the pandemic.
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Brenner EJ, Ungaro RC, Gearry RB, et al. Corticosteroids, But Not TNF Antagonists, Are Associated With Adverse COVID-19 Outcomes in Patients With Inflammatory Bowel Diseases: Results From an International Registry [published online ahead of print, 2020 May 18]. Gastroenterology. 2020;S0016-5085(20)30655-7. doi:10.1053/j.gastro.2020.05.032
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